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  1. Science & Research (NCTR)

NCTR Participation in 2024 FDA Foods Program Regulatory Science Conference

Forging New Frontier: Charting a Path Forward for Advancing One Health Research - September 10-11, 2024

The FDA Foods Program Regulatory Science Conference (FPRSC) was held in-person September 10-11, 2024, at the FDA Center for Food Safety and Applied Nutrition (CFSAN) Campus in College Park, Maryland. The conference offered an opportunity to showcase the important, mission-relevant research being carried out across the Foods Program and provided a platform for FDA staff to share their technical expertise and network with colleagues. The conference also included poster presentations from different FDA centers, including NCTR.

The following scientific topics were presented by NCTR staff:

Oral Presentations

  • "State of the Science" — Tucker Patterson, Ph.D., NCTR Director
  • "Sex-Based Differences in the Immunotoxicity of Silver Nanoparticles" (B. Canup, P. Rogers, A. Paredes, W. Manheng, B. Lyn-Cook, and T. Fahmi)
  • "Development of Severe NASH-Like Liver Injury by Chronic Administration of a High-fat and High-sucrose Diet in Mice" (R.A. Willett, V.P. Tryndyak, J.H. Hanks, S.K. Nagumalli, M.I. Avigan, G. Gamboa da Costa, F.A. Beland, I. Rusyn, and I.P. Pogribny)

Poster Presentation Abstracts

  • "Survey of Immunotoxicity of Titanium Dioxide" (B. Canup, P. Rogers, N. Twaddle, A. Paredes, W. Manheng, B. Lyn-Cook, and T. Fahmi)
  • "Metabolism and Toxicity of Sudan Azo Dyes: Insights from Commensal Bacteria Studies" (H. Chen and J. Sun)
  • "WGS Analyses: Room for the Benchtop?" (K. Feye, D. Sopovski, J. Revollo, J. Miranda-Colon, D. Gudeta, J. Han, and S. Foley)
  • "Coupling Antitoxins and Blue/White Screening with an Inducible Toxin Counter-Selection Strategy for Salmonella spp. and E. coli Plasmid Cure" (D.D. Gudeta and S.L. Foley)
  • "Verapamil Inhibits Inorganic Arsenic-Induced Apoptosis, but May Cause Cardiotoxicity in the Presence of Inorganic Arsenic that is Alleviated by Acetyl l-Carnitine in Zebrafish Embryos" (J. Kanungo, C. Silva, N. Twaddle, and S. Fitzpatrick)
  • "Novel Mechanism of Action of the Gentamicin-Resistance Protein, GrdA from Salmonella enterica" (A.A. Khan, A. Hikal, S. Foley, and S. Zhao)
  • "Evaluation and Comparison of In Vitro Permeation Testing (IVPT) in Alternative Skin Models and Excised Human Skin" (S.M.S. Modaresi, A.T. Salminen, K.J. Davis, R.P. Felton, J. Sun, F.A. Beland, K. Derr, P.C. Brown, M. Ferrer, L.M. Katz, N.C. Kleinstreuer, J. Leshin, P. Manga, N. Sadrieh, M. Xia, S.C. Fitzpatrick, and L. Camacho)
  • "Chicken Juice Enhances C. jejuni Biofilm Formation with Distinct Morphological Features and Altered Protein Expression" (K. Sung, M. Park, J. Chon, O. Kweon, A. Paredes, and S.A. Khan)

  • "Robust Transcriptomic-based Signature Model for Detecting NASH-like Liver Damage in Mice" (V.P. Tryndyak, R.A. Willett, K. Dreval, M.I. Avigan, I. Rusyn, F.A. Beland, and I.P. Pogribny)

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