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  4. CPG Sec 540.525 Scombrotoxin (Histamine)-forming Fish and Fishery Products – Decomposition and Histamine (CPG 7108.24)
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COMPLIANCE POLICY GUIDE (CPG)

CPG Sec 540.525 Scombrotoxin (Histamine)-forming Fish and Fishery Products – Decomposition and Histamine (CPG 7108.24) November 2024

Download the Final Compliance Policy Guide (CPG) Read the Federal Register Notice
Final
Docket Number:
FDA-2021-D-0367
Issued by:
Guidance Issuing Office
Human Foods Program
Office of Inspections and Investigations

The purpose of this compliance policy guide (CPG) is to provide guidance for FDA staff on adulteration associated with decomposition and/or histamine identified during surveillance sampling and testing of fish and fishery products susceptible to histamine formation.  

In general, FDA’s guidance documents do not establish legally enforceable responsibilities. Instead, guidances describe our current thinking on a topic and should be viewed only as recommendations, unless specific regulatory or statutory requirements are cited. The use of the word should in FDA guidances means that something is suggested or recommended, but not required.

Download the Compliance Policy Guide (CPG)

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All written comments should be identified with this document's docket number: FDA-2021-D-0367.

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