Laboratory Information Bulletins
FDA posts Laboratory Information Bulletins of interest to the public.
This is a list of the most recent LIBs available online.
For LIBs published before 2018, please use the Requesting a Laboratory Information Bulletin (LIB) page.
| LIB Number | LIB Title |
|---|---|
| LIB4692 | Update to LIB No. 4550 Quantitation of Nicotine in Tobacco Products |
| LIB4631 | Analysis of Oxytetracycline, Chloramphenicol, and Florfenicol in Lobster and Crab Tissue Using Liquid Chromatography - Triple Quadrupole Mass Spectrometry (LC-MS/MS) |
| LIB4632 | Application of an On-Line Restricted Access Material (RAM)/Liquid Chromatography/Tandem Mass Spectrometry Method for the Rapid Determination of Veterinary Drug Residues in Fish |
| LIB4633 | Qualitative analysis of color additives in hair conditioner products by UPLC with Photo Diode Array detection |
| LIB4634 | Quantitative Determination of Oxytetracycline in Six Aquaculture Commodities by Rapid and Sensitive UHPLC-MS/MS |
| LIB4635 | Determination of Crude Protein Content in Diverse Standard Reference Materials and Infant Formulas Using the Dumas Combustion Method |
| LIB4636 | A Rapid Liquid Chromatography-Fluorescence Detection (UPLC/FLD) for the Quantitative Analysis of Avermectin Residues in Salmon and Trout |
| LIB4637 | Determination and Confirmation Analysis of Lufenuron Residues in Salmon and Trout Tissue by Liquid Chromatography-Tandem Mass Spectrometry Atmospheric Pressure Chemical Ionization (LC-MS/MS APCI) |
| LIB4638 | Validation of an Analytical Method for the Detection and Quantification of Glyphosate and Related Residues in Food |
| LIB4639 | Detection of aequorin-2 protein in dietary supplements using mass spectrometry protein sequence analysis |
| LIB4640 | Sensitive and Accurate Multi-Class Veterinary Drug Analytical Method Validation for Shell Eggs Using Liquid Chromatography-Tandem Mass Spectrometry |
| LIB4641 | Identification of a Universal Enrichment Broth for Simultaneous Enrichment of Salmonella spp., E. coli O157:H7 and Listeria monocytogenes |
| LIB4642 | Multiclass Screening Method Using Automated Solid-Phase Extraction Directly Coupled to a Mass Spectrometer for Drug Residues in Honey |
| LIB4643 | Color Additive Analysis in Foods and Cosmetics using UPLC with Extended Photo-Diode Array Detection |
| LIB4644 | Analysis of Avermectin Residues in Game Meats (Bison, Deer, Elk, and Rabbit) by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) |
| LIB4645 | Expanding LIB 4615 and LIB4616 to include additional chemical contaminants in the analysis of tilapia, salmon, eel and shrimp using Liquid Chromatography High-Resolution Mass Spectrometry (LC-HRMS) |
| LIB4646 | Triphenylmethane Dye Residue Analysis in Raw and Processed Aquaculture Products by AOAC Official Method of Analysis 2012.25 |
| LIB4647 | Analysis of Peptide Antibiotics in Milk using High Resolution Mass Spectrometry (HRMS) |
| LIB4648 | Determination of Pentobarbital in Tallow Using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) |
| LIB4649 | 2017 update of the matrix extension data for the VIDAS Salmonella (SLM) AOAC Official Method 2004.03 captured in the Field Accomplishment Computerized Tracking System (FACTS) |
| LIB4650 | Pesticide matrix extension validation for grasshoppers/chapulines using QuEChERS extraction with GC-MS/MS and LC-MS/MS detection |
| LIB4651 | Rapid Determination of Hypoglycin A in Ackee by Liquid Chromatography/Tandem mass spectrometry |
| LIB4652 | Screen for Steroids using Gas Chromatography-Mass Spectrometry |
| LIB4653 | Multiclass Veterinary Drug Residue Method for Aquaculture Products Using LC-MS/MS |
| LIB4654 | Quantitative Determination of Bisphenol-A in Tuna using Liquid Chromatography Tandem Mass Spectrometry |
| LIB4655 | Evaluation of the QIAcube and the MicroSEQ D2 LSU rDNA system for the identification of fungal isolates from medical products |
| LIB4656 | Report of a Single Laboratory Validation Study: Platform Extension of the Simplex Real-time PCR Method for Detection of Prohibited Materials in Animal Feed |
| LIB4657 | A Simplex Real-time PCR Method for Detection of Prohibited Materials in Animal Feed on the Applied Biosystems 7500 Fast System |
| LIB4658 | Listeria monocytogenes Identification by Subtyping MALDI-TOF MS Biotyper Analysis |
| LIB4659 | LC-MS/MS Determination of Gyromitrin in Mushrooms as a Method to Identify False Morel Mushrooms |
| LIB4660R | Multiclass, Multiresidue Method for the Quantitation and Confirmation of over 110 Vet Drugs in Game Meat (Bison, Deer, Elk, and Rabbit) by Rapid Polarity Switching Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) (CARTS Project No. IR01040) |
| LIB4661 | Review of the validation status of regulated matrices for the VIDAS™ Salmonella (SLM) AOAC Official Method 2004.03: 2018 Matrix Extension Data |
| LIB4662 | Extraction of light and heavy filth from lipstick |
| LIB4663 | Review of the VIDAS-Listeria (AOAC OMA 999.06) method-matrix extension data from FDA regulatory activities from 2016 through 2019 |
| LIB4664a | Comparing the VIDAS-Salmonella (SLM) and VIDAS-Salmonella Easy (SLM Easy) Methods using Method-Matrix Extension Validation Data |
| LIB4665 | Determination of pentobarbital in ingredients of animal origin and in finished pet foods using liquid chromatography tandem mass spectrometry (LC-MS/MS) CARTS: IR01702 |
| LIB4666 | Optimization of a Positive Control for the Feed Extraction and Real-time PCR Method Used in the Bovine Spongiform Encephalopathy Program |
| LIB4667 | Enhancements to LIB 4560 to include method modifications, and additional drug residues in honey using LC-MS/MS |
| LIB4668 | Appropriateness of the VIDAS Listeria Method (AOAC Official Method 999.06) for Screening Crab Meat Enrichments for the Presence of Listeria monocytogenes |
| LIB4669 | Evaluation of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) for the Rapid Identification of Fungi |
| LIB4670 | Quantitation of Methanol, Ethanol and Isopropanol in Gel Hand Sanitizer Product by Gas Chromatography-Flame Ionization Detection (GC-FID) |
| LIB4671 | Confirmatory Analysis of Honey for Sildenafil and Tadalafil by LC-MS/MS |
| LIB4672 | A Single Lab Validation for Species Identification of Campylobacter jejuni utilizing the VITEK-MS system |
| LIB4673 | Updates to LIBs #4615/4616 Screening Method for Veterinary Drug Residues using LC-HRMS: Validation in Shrimp |
| LIB4674 | Identification and Quantitation of Benzene Impurity in Sunscreen Product by Headspace Gas Chromatography-Mass Spectrometry Detection (HSGC-MS) |
| LIB4675 | Identification and Quantitation of Oxybenzone, Octocrylene, Avobenzone, Octinoxate, Homosalate and Octisalate in Sunscreen Products by High Performance Liquid Chromatography-Diode Array Detection (HPLC-DAD) |
| LIB4676 | Validation of an LC-MS/MS Method for the Determination of 26 Per- and Polyfluoroalkyl Substances (PFAS) in Animal Foods |
| LIB4678 | Modifications to LIB 4597 for the analysis of nitrofuran metabolites and chloramphenicol in aquaculture products using LC-MS/MS |
| LIB4679 | Detection of Fluorescent Brightening Agents Tinopal CBS-X and FB28 in food matrices using UPLC with tandem PDA/FLR detection |
| LIB4680 | Single Laboratory Validation for the Determination of Six Biogenic Amines in Canned Tuna with Liquid-Liquid Extraction and Liquid Chromatography- Tandem Mass Spectrometry |
| LIB4681 | New Method to Power High Frequency Tanning Lamps with Varied Parameters for Measuring Ultraviolet Radiation Lamp Output Power |
| LIB4682 | Modifications to LIB 4597 for the analysis of nitrofuran metabolites and chloramphenicol in aquaculture products using LC-MS/MS |