Vaccines Research

Bacterial Polysaccharides

• Characterization of Bacterial Glycoconjugates and Development of Associated Vaccine Technologies
  Wille Vann, PhD
• Evaluating the Host and Microbial Factors That Impact the Efficacy of Polysaccharide Vaccines
  Mustafa Akkoyunlu, MD, PhD
• Biomarkers of Vaccine Safety and Effectiveness for Encapsulated Bacterial Pathogens
  Margaret C. Bash, MD, MPH
• Studying the Structure of Carbohydrates in Order to Better Understand Bacterial Vaccines and Pathogens
  John F. Cipollo, PhD
• Improvement of Biological Product Quality by Application of New Technologies to Characterize of Vaccines and Blood Products: NMR Spectroscopy and Light Scattering
  Darón I. Freedberg, PhD

Mucosal Pathogens and Cellular Immunology

• Novel Methods to Detect Malaria Biomarkers for Evaluation of Vaccine Safety and Efficacy
  Heather J. Painter, PhD
• Methods to Predict and Improve Efficacy of Vaccines Against Bacterial Pathogens
  Siobhan C. Cowley, PhD
• New Ways to Predict How Well Vaccines Protect Against Tuberculosis, Tularemia and Other Bacteria That Live Inside Cells
  Karen Elkins, PhD

Respiratory & Special Pathogens

• Improving Evaluation of Bacterial Vaccines
  Drusilla Burns, PhD
• Developing and Evaluating Animal Models for Studying the Safety and Efficacy of Vaccines Against Anthrax, Staphylococcal Infections, and Pertussis
  Todd Merkel, PhD
• Biomarkers of Vaccine Safety and Efficacy for Diphtheria Vaccines
  Michael Schmitt, PhD

DNA and Hepatitis Viruses

• Gastrointestinal Viruses: Understanding Diversity and Immune Responses to Inform Vaccine Design
  Gabriel I. Parra, PhD
• Development of Quantitative Assays to Evaluate the Safety of Cell Substrates and Vaccines
  Keith Peden, PhD
• Development of Assays of Defined Sensitivity for the Regulatory Management of Novel Cell Substrates
  Andrew Lewis, MD
• New Approaches to the Development and Evaluation of Vaccines Against Hepatitis Viruses
  Marian Major, PhD
• DNA Virus Vaccines and Vectors
  Jerry Weir, PhD

Methods Development

• Evaluation of the Quality of Viral Vaccines Based on Molecular Consistency
  Konstantin M. Chumakov, PhD

Pediatric & Respiratory Viral Diseases

• Influenza neuraminidase antigenicity and efficacy in vaccines
  Robert Daniels, PhD
• Supporting the Production of Safe and Effective Influenza Vaccines
  Zhiping Ye, MD, PhD
• Developing Tests to Detect Evidence of Protective Immune Responses Generated by Vaccines for Respiratory Viruses That Infect Infants, Children and the Elderly
  Judy Beeler, MD

Retrovirus Research

• HIV Influenza And Smallpox Vaccines: Development of New Assays and Animal Models for Evaluation of Vaccine Safety and Efficacy
  Hana Golding, PhD
• Investigating Viruses in Cells Used to Make Vaccines; and Evaluating the Potential Threat Posed by Transmission of Viruses to Humans
  Arifa Khan, PhD

Vector Borne Viral Diseases

• Understanding the Interplay Between Host Immunity and Viral Factors for Rational Design of Vaccines Against Vector-Borne Viral Pathogens
  Tony Wang, PhD

Immunology

• Evaluating New Approaches to Developing AIDS Vaccines by Creating Virus-like Particles that Display HIV Antigens or by Using Live, Attenuated (Weakened), non-HIV Viruses to Express HIV Proteins
  Ira Berkower, MD
• Virus Entry and Its Inhibition by Antibodies: Studies to Aid the Development and Evaluation of Vaccines that Protect against Viral Infectious Diseases
  Carol Weiss, MD