Antimicrobial Resistance
Determining antimicrobial resistance and virulence mechanisms of foodborne and other pathogens
Antimicrobial resistance (AMR)—the ability of a microorganism (bacteria, virus, fungi, parasite) to resist the effects of a drug—has become a substantial public health concern in recent years. According to the Centers for Disease Control (CDC), more than 2.8 million antimicrobial-resistant infections occur in the U.S. each year, and more than 35,000 people die as a result. Because AMR remains a global public health threat, it is one of FDA's Focus Areas of Regulatory Science.
Presentations/Conferences on AMR-Related Research by NCTR Scientists
- FDA Grand Rounds: "The Plasmid Puzzle—Finding Solutions in Salmonella" (Presentation recorded via Zoom on July 13, 2023)
- FDA Grand Rounds: "Salmonella and Escherichia coli: Challenges Along the One Health Continuum" (Presentation recorded via Zoom on July 11, 2024)
- NCTR Research Highlight: NCTR Staff Present at International Veterinary Medicine Conference
Posters on AMR-Related Research by NCTR Scientists
| Poster PDF | Title | Authors |
|---|---|---|
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Characterization of Efflux Pumps and its Role on the Intrinsic Resistance in Antimicrobial Resistant Salmonella enterica from Clinical and Food Samples. | Khan A., Zhao A., and Nawaz M. |
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Evaluating Salmonella serovars for Antibiotic Resistance Genotypes and Virulence Factors. | Sopovski D., Feye K., Gudeta D., Han J., Zhao S., and Foley S. |
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Evaluation of Gentamycin Resistant Phenotypes in Genotypically Susceptible Salmonella enterica Isolates. | Khan A., Xie S., Spropovski D., Foley S., and Feye K. |
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The Plasmid Puzzle: Challenges for Salmonella Monitoring. Watch the Grand Rounds Presentation |
Feye K., Sopovski D., Revollo J., Miranda-Colon J., Gudeta D., Han J., and Foley S. |
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Salmonella enterica serovar Schwarzengrund: Distribution, Virulence and Antimicrobial Resistance | Foley S.L., Han J., Sopovski D., Khajanchi B.K., and Sanad Y.M. |
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Simple Blue-White Screening Strategy for Salmonella Plasmid Curing. | Gudeta D.D. and Foley S.L. |
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Time-Course Proteome Analyses of Air-Liquid Interface Biofilm of Pseudomonas aeruginosa PA14. | Sung K., Park M., Chon J., Kweon O., and Khan S. |
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Versatile Allelic Replacement and Self-Excising Integrative Vectors for Salmonella Plasmid Genome Studies. | Gudeta D.D. and Foley S.L. |