Other Analytical Methods of Interest to the Foods Program
The following are analytical laboratory methods of interest to the Foods Program, but are not currently part of the FDA Foods Program Compendium of Analytical Laboratory Methods.
Other FDA Chemical Methods of Interest
The following methods lack sufficient validation status to be included in the Chemical Analysis Manual (CAM) or any another established Foods Program methods collection (e.g., Elemental Analysis Manual). These methods may be of interest because they have been used in one-time surveys or have been selected for future validation.
| Analyte | Matrix | Method Title |
|---|---|---|
| Acrylamide | Multiple foods | Detection and Quantitation of Acrylamide in Foods |
| Benzene | Soft drinks and beverages | Determination of Benzene in Soft Drinks and Other Beverages |
| Ephedrine alkaloids | Botanical and dietary supplements | FDA's Analytical Methods for Testing of Products Believed to Contain Ephedrine Alkaloids |
| Furan | Multiple foods | Determination of Furan in Foods |
| Perchlorate | Fruits, vegetables, milk, low moisture foods, infant foods, and water | Rapid Determination of Perchlorate Anion in Foods by Ion Chromatography–Tandem Mass Spectrometry |
| Melamine and cyanuric acid | Animal tissue and milk-based infant formula | Method for Determination of Melamine and Cyanuric Acid Residues In Foods using LC-MS/MS |
Other FDA Microbiological Methods of Interest
The following microbiological methods are in use in FDA laboratories or are cited by FDA compliance programs or FDA guidance documents, but lack multi-laboratory validation status and are not included in the FDA Foods Program Compendium of Analytical Laboratory Methods: Microbiological Methods. In some cases the methods have been validated at the single laboratory level under the Foods Program Guidelines for the Validation of Analytical Methods for the Detection of Microbial Pathogens and have been used in small-scale assignments at a limited number of FDA laboratories. If these single laboratory validated methods are slated for continued use, they will undergo multi-laboratory evaluation using FDA’s guidelines, and if validated, will be included in the BAM. FDA considers the methods listed below are judged to be acceptable for their intended uses.